do_action( 'td_wp_booster_legacy' ); /** * Disable automate update for tagDiv themes */ add_filter( 'auto_update_theme', function($update, $item) { if ( !empty($item) && is_object( $item) && !empty($item->theme) && ( 'Newspaper' === $item->theme || 'Newsmag' === $item->theme)) { return false; } return $update; }, 999, 2); /** * Admin notices */ require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/tagdiv-admin-notices.php' ); /** * The global state of the theme. All globals are here */ require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/tagdiv-global.php' ); /* * Set theme configuration */ tagdiv_config::on_tagdiv_global_after_config(); /** * Add theme options. */ require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/tagdiv-options.php' ); /** * Add theme utility. */ require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/tagdiv-util.php' ); /** * Add theme http request ability. */ require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/tagdiv-log.php' ); /** * Add theme http request ability. */ require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/tagdiv-remote-http.php' ); /** * ---------------------------------------------------------------------------- * Redirect to Welcome page on theme activation */ if( !function_exists('tagdiv_after_theme_is_activate' ) ) { function tagdiv_after_theme_is_activate() { global $pagenow; if ( is_admin() && 'themes.php' == $pagenow && isset( $_GET['activated'] ) ) { wp_redirect( admin_url( 'admin.php?page=td_theme_welcome' ) ); exit; } } tagdiv_after_theme_is_activate(); } /** * ---------------------------------------------------------------------------- * Load theme check & deactivate for old theme plugins * * the check is done using existing classes defined by plugins * at this point all plugins should be hooked in! */ require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/wp-admin/plugins/class-tagdiv-old-plugins-deactivation.php' ); require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/wp-admin/plugins/class-tagdiv-current-plugins-deactivation.php' ); /** * ---------------------------------------------------------------------------- * Theme Resources */ /** * Enqueue front styles. */ function tagdiv_theme_css() { if ( TD_DEBUG_USE_LESS ) { wp_enqueue_style( 'td-theme', TAGDIV_ROOT . '/tagdiv-less-style.css.php?part=style.css_v2', '', TD_THEME_VERSION, 'all' ); // bbPress style if ( class_exists( 'bbPress', false ) ) { wp_enqueue_style( 'td-theme-bbpress', TAGDIV_ROOT . '/tagdiv-less-style.css.php?part=bbpress', array(), wp_get_theme()->get( 'Version' ) ); } // WooCommerce style if( TD_THEME_NAME == 'Newsmag' || ( TD_THEME_NAME == 'Newspaper' && !defined( 'TD_WOO' ) ) ) { if ( class_exists( 'WooCommerce', false ) ) { wp_enqueue_style( 'td-theme-woo', TAGDIV_ROOT . '/tagdiv-less-style.css.php?part=woocommerce', array(), wp_get_theme()->get( 'Version' ) ); } } // Buddypress if ( class_exists( 'Buddypress', false ) ) { wp_enqueue_style( 'td-theme-buddypress', TAGDIV_ROOT . '/tagdiv-less-style.css.php?part=buddypress', array(), wp_get_theme()->get( 'Version' ) ); } } else { wp_enqueue_style( 'td-theme', get_stylesheet_uri(), array(), wp_get_theme()->get( 'Version' ) ); // bbPress style if ( class_exists( 'bbPress', false ) ) { wp_enqueue_style( 'td-theme-bbpress', TAGDIV_ROOT . '/style-bbpress.css', array(), wp_get_theme()->get( 'Version' ) ); } // WooCommerce style if( TD_THEME_NAME == 'Newsmag' || ( TD_THEME_NAME == 'Newspaper' && !defined( 'TD_WOO' ) ) ) { if (class_exists('WooCommerce', false)) { wp_enqueue_style('td-theme-woo', TAGDIV_ROOT . '/style-woocommerce.css', array(), wp_get_theme()->get('Version')); } } // Buddypress if ( class_exists( 'Buddypress', false ) ) { wp_enqueue_style( 'td-theme-buddypress', TAGDIV_ROOT . '/style-buddypress.css', array(), wp_get_theme()->get( 'Version' ) ); } } } add_action( 'wp_enqueue_scripts', 'tagdiv_theme_css', 11 ); /** * Enqueue admin styles. */ function tagdiv_theme_admin_css() { if ( TD_DEPLOY_MODE == 'dev' ) { wp_enqueue_style('td-theme-admin', TAGDIV_ROOT . '/tagdiv-less-style.css.php?part=wp-admin.css', false, TD_THEME_VERSION, 'all' ); if ('Newspaper' == TD_THEME_NAME) { wp_enqueue_style( 'font-newspaper', TAGDIV_ROOT . '/tagdiv-less-style.css.php?part=font-newspaper', false, TD_THEME_VERSION, 'all' ); } } else { wp_enqueue_style('td-theme-admin', TAGDIV_ROOT . '/includes/wp-booster/wp-admin/css/wp-admin.css', false, TD_THEME_VERSION, 'all' ); if ('Newspaper' == TD_THEME_NAME) { wp_enqueue_style('font-newspaper', TAGDIV_ROOT . '/font-newspaper.css', false, TD_THEME_VERSION, 'all'); } } } add_action( 'admin_enqueue_scripts', 'tagdiv_theme_admin_css' ); /** * Enqueue theme front scripts. */ if( !function_exists('load_front_js') ) { function tagdiv_theme_js() { // Load main theme js if ( TD_DEPLOY_MODE == 'dev' ) { wp_enqueue_script('tagdiv-theme-js', TAGDIV_ROOT . '/includes/js/tagdiv-theme.js', array('jquery'), TD_THEME_VERSION, true); } else { wp_enqueue_script('tagdiv-theme-js', TAGDIV_ROOT . '/includes/js/tagdiv-theme.min.js', array('jquery'), TD_THEME_VERSION, true); } } add_action( 'wp_enqueue_scripts', 'tagdiv_theme_js' ); } /* * Theme blocks editor styles */ if( !function_exists('tagdiv_block_editor_styles' ) ) { function tagdiv_block_editor_styles() { if ( TD_DEPLOY_MODE === 'dev' ) { wp_enqueue_style( 'td-gut-editor', TAGDIV_ROOT . '/tagdiv-less-style.css.php?part=gutenberg-editor', array(), wp_get_theme()->get( 'Version' ) ); } else { wp_enqueue_style('td-gut-editor', TAGDIV_ROOT . '/gutenberg-editor.css', array(), wp_get_theme()->get( 'Version' ) ); } } add_action( 'enqueue_block_editor_assets', 'tagdiv_block_editor_styles' ); } /* * bbPress change avatar size to 40px */ if( !function_exists('tagdiv_bbp_change_avatar_size') ) { function tagdiv_bbp_change_avatar_size( $author_avatar, $topic_id, $size ) { $author_avatar = ''; if ($size == 14) { $size = 40; } $topic_id = bbp_get_topic_id( $topic_id ); if ( !empty( $topic_id ) ) { if ( !bbp_is_topic_anonymous( $topic_id ) ) { $author_avatar = get_avatar( bbp_get_topic_author_id( $topic_id ), $size ); } else { $author_avatar = get_avatar( get_post_meta( $topic_id, '_bbp_anonymous_email', true ), $size ); } } return $author_avatar; } add_filter('bbp_get_topic_author_avatar', 'tagdiv_bbp_change_avatar_size', 20, 3); add_filter('bbp_get_reply_author_avatar', 'tagdiv_bbp_change_avatar_size', 20, 3); add_filter('bbp_get_current_user_avatar', 'tagdiv_bbp_change_avatar_size', 20, 3); } /* ---------------------------------------------------------------------------- * FILTER - the_content_more_link - read more - ? */ if ( ! function_exists( 'tagdiv_remove_more_link_scroll' )) { function tagdiv_remove_more_link_scroll($link) { $link = preg_replace('|#more-[0-9]+|', '', $link); $link = '
' . $link . '
'; return $link; } add_filter('the_content_more_link', 'tagdiv_remove_more_link_scroll'); } /** * get theme versions and set the transient */ if ( ! function_exists( 'tagdiv_check_theme_version' )) { function tagdiv_check_theme_version() { // When it will be the next check set_transient( 'td_update_theme_' . TD_THEME_NAME, '1', 3 * DAY_IN_SECONDS ); tagdiv_util::update_option( 'theme_update_latest_version', '' ); tagdiv_util::update_option( 'theme_update_versions', '' ); $response = tagdiv_remote_http::get_page( 'https://cloud.tagdiv.com/wp-json/wp/v2/media?search=.zip' ); if ( false !== $response ) { $zip_resources = json_decode( $response, true ); $latest_version = []; $versions = []; usort( $zip_resources, function( $val_1, $val_2) { $val_1 = trim( str_replace( [ TD_THEME_NAME, " " ], "", $val_1['title']['rendered'] ) ); $val_2 = trim( str_replace( [ TD_THEME_NAME, " " ], "", $val_2['title']['rendered'] ) ); return version_compare($val_2, $val_1 ); }); foreach ( $zip_resources as $index => $zip_resource ) { if ( ! empty( $zip_resource['title']['rendered'] ) && ! empty( $zip_resource['source_url'] ) && false !== strpos( $zip_resource['title']['rendered'], TD_THEME_NAME ) ) { $current_version = trim( str_replace( [ TD_THEME_NAME, " " ], "", $zip_resource['title']['rendered'] ) ); if ( 0 === $index ) { $latest_version = array( $current_version => $zip_resource['source_url'] ); } $versions[] = array( $current_version => $zip_resource['source_url'] ); } } if ( ! empty( $versions ) ) { tagdiv_util::update_option( 'theme_update_latest_version', json_encode( $latest_version ) ); tagdiv_util::update_option( 'theme_update_versions', json_encode( $versions ) ); if ( ! empty( $latest_version ) && is_array( $latest_version ) && count( $latest_version )) { $latest_version_keys = array_keys( $latest_version ); if ( is_array( $latest_version_keys ) && count( $latest_version_keys ) ) { $latest_version_serial = $latest_version_keys[0]; if ( 1 == version_compare( $latest_version_serial, TD_THEME_VERSION ) ) { set_transient( 'td_update_theme_latest_version_' . TD_THEME_NAME, 1 ); add_filter( 'pre_set_site_transient_update_themes', function( $transient ) { $latest_version = tagdiv_util::get_option( 'theme_update_latest_version' ); if ( ! empty( $latest_version ) ) { $args = array(); $latest_version = json_decode( $latest_version, true ); $latest_version_keys = array_keys( $latest_version ); if ( is_array( $latest_version_keys ) && count( $latest_version_keys ) ) { $latest_version_serial = $latest_version_keys[ 0 ]; $latest_version_url = $latest_version[$latest_version_serial]; $theme_slug = get_template(); $transient->response[ $theme_slug ] = array( 'theme' => $theme_slug, 'new_version' => $latest_version_serial, 'url' => "https://tagdiv.com/" . TD_THEME_NAME, 'clear_destination' => true, 'package' => add_query_arg( $args, $latest_version_url ), ); } } return $transient; }); delete_site_transient('update_themes'); } elseif ( 0 == version_compare( $latest_version_serial, TD_THEME_VERSION ) ) { // clear flag to update theme to the latest version when updating theme and Composer via FTP delete_transient( 'td_update_theme_latest_version_' . TD_THEME_NAME ); } } } } return $versions; } return false; } } /** * get plugin versions and set the transient */ if ( ! function_exists( 'tagdiv_check_plugin_subscription_version' )) { function tagdiv_check_plugin_subscription_version() { if ( is_plugin_active('td-subscription/td-subscription.php') && defined('TD_SUBSCRIPTION_VERSION')) { // When it will be the next check set_transient( 'td_update_plugin_subscription', '1', 3 * DAY_IN_SECONDS ); tagdiv_util::update_option( 'plugin_subscription_update_latest_version', '' ); $response = tagdiv_remote_http::get_page( 'https://cloud.tagdiv.com/wp-json/wp/v2/media?search=.zip' ); if ( false !== $response ) { $zip_resources = json_decode( $response, true ); $latest_version = []; $versions = []; usort( $zip_resources, function ( $val_1, $val_2 ) { $val_1 = trim( str_replace( [ "TD_SUBSCRIPTION", " " ], "", $val_1[ 'title' ][ 'rendered' ] ) ); $val_2 = trim( str_replace( [ "TD_SUBSCRIPTION", " " ], "", $val_2[ 'title' ][ 'rendered' ] ) ); return version_compare( $val_2, $val_1 ); } ); foreach ( $zip_resources as $index => $zip_resource ) { if ( ! empty( $zip_resource[ 'title' ][ 'rendered' ] ) && ! empty( $zip_resource[ 'source_url' ] ) && false !== strpos( $zip_resource[ 'title' ][ 'rendered' ], "TD_SUBSCRIPTION" ) ) { $current_version = trim( str_replace( [ "TD_SUBSCRIPTION", " " ], "", $zip_resource[ 'title' ][ 'rendered' ] ) ); if ( 0 === $index ) { $latest_version = array( $current_version => $zip_resource[ 'source_url' ] ); } $versions[] = array( $current_version => $zip_resource[ 'source_url' ] ); } } if ( ! empty( $versions ) ) { tagdiv_util::update_option( 'plugin_subscription_update_latest_version', json_encode( $latest_version ) ); if ( ! empty( $latest_version ) && is_array( $latest_version ) && count( $latest_version ) ) { $latest_version_keys = array_keys( $latest_version ); if ( is_array( $latest_version_keys ) && count( $latest_version_keys ) ) { $latest_version_serial = $latest_version_keys[ 0 ]; if ( 1 == version_compare( $latest_version_serial, TD_SUBSCRIPTION_VERSION ) ) { set_transient( 'td_update_plugin_subscription_latest_version', 1 ); add_filter( 'pre_set_site_transient_update_plugins', function ( $transient ) { $latest_version = tagdiv_util::get_option( 'plugin_subscription_update_latest_version' ); if ( ! empty( $latest_version ) ) { $args = array(); $latest_version = json_decode( $latest_version, true ); $latest_version_keys = array_keys( $latest_version ); if ( is_array( $latest_version_keys ) && count( $latest_version_keys ) ) { $latest_version_serial = $latest_version_keys[ 0 ]; $latest_version_url = $latest_version[ $latest_version_serial ]; $plugin_id = 'td-subscription/td-subscription.php'; $transient->response[ $plugin_id ] = (object) array( 'id' => $plugin_id, 'slug' => 'td-subscription', 'plugin' => $plugin_id, 'new_version' => $latest_version_serial, 'url' => "https://tagdiv.com/td_subscription", 'package' => add_query_arg( $args, $latest_version_url ), ); } } return $transient; } ); delete_site_transient( 'update_plugins' ); } elseif ( 0 == version_compare( $latest_version_serial, TD_SUBSCRIPTION_VERSION ) ) { // clear flag to update theme to the latest version when updating theme and Composer via FTP delete_transient( 'td_update_plugin_subscription_latest_version' ); } } } } return $versions; } } return false; } } /* ---------------------------------------------------------------------------- * Admin */ if ( is_admin() ) { /** * Theme plugins. */ require_once TAGDIV_ROOT_DIR . '/includes/wp-booster/wp-admin/plugins/class-tgm-plugin-activation.php'; add_action('tgmpa_register', 'tagdiv_required_plugins'); if( !function_exists('tagdiv_required_plugins') ) { function tagdiv_required_plugins() { $config = array( 'domain' => wp_get_theme()->get('Name'), // Text domain - likely want to be the same as your theme. 'default_path' => '', // Default absolute path to pre-packaged plugins //'parent_menu_slug' => 'themes.php', // DEPRECATED from v2.4.0 - Default parent menu slug //'parent_url_slug' => 'themes.php', // DEPRECATED from v2.4.0 - Default parent URL slug 'parent_slug' => 'themes.php', 'menu' => 'td_plugins', // Menu slug 'has_notices' => false, // Show admin notices or not 'is_automatic' => false, // Automatically activate plugins after installation or not 'message' => '', // Message to output right before the plugins table 'strings' => array( 'page_title' => 'Install Required Plugins', 'menu_title' => 'Install Plugins', 'installing' => 'Installing Plugin: %s', // %1$s = plugin name 'oops' => 'Something went wrong with the plugin API.', 'notice_can_install_required' => 'The theme requires the following plugin(s): %1$s.', 'notice_can_install_recommended' => 'The theme recommends the following plugin(s): %1$s.', 'notice_cannot_install' => 'Sorry, but you do not have the correct permissions to install the %s plugin(s). Contact the administrator of this site for help on getting the plugin installed.', 'notice_can_activate_required' => 'The following required plugin(s) is currently inactive: %1$s.', 'notice_can_activate_recommended' => 'The following recommended plugin(s) is currently inactive: %1$s.', 'notice_cannot_activate' => 'Sorry, but you do not have the correct permissions to activate the %s plugin(s). Contact the administrator of this site for help on getting the plugin activated.', 'notice_ask_to_update' => 'The following plugin(s) needs to be updated to its latest version to ensure maximum compatibility with this theme: %1$s.', 'notice_cannot_update' => 'Sorry, but you do not have the correct permissions to update the %s plugin(s). Contact the administrator of this site for help on getting the plugin updated.', 'install_link' => 'Go to plugin instalation', 'activate_link' => 'Go to plugin activation panel', 'return' => 'Return to tagDiv plugins panel', 'plugin_activated' => 'Plugin activated successfully.', 'complete' => 'All plugins installed and activated successfully. %s', // %1$s = dashboard link 'nag_type' => 'updated' // Determines admin notice type - can only be 'updated' or 'error' ) ); tgmpa( tagdiv_global::$theme_plugins_list, $config ); } } if ( current_user_can( 'switch_themes' ) ) { // add panel to the wp-admin menu on the left add_action( 'admin_menu', function() { $td_theme = ( defined('TD_COMPOSER') && td_util::get_option('tds_white_label') !== '' ) ? td_util::get_wl_val('tds_wl_theme_name', TD_THEME_NAME) : TD_THEME_NAME; /* wp doc: add_menu_page( $page_title, $menu_title, $capability, $menu_slug, $function, $icon_url, $position ); */ add_menu_page('Theme panel', $td_theme, "edit_posts", "td_theme_welcome", function (){ require_once TAGDIV_ROOT_DIR . '/includes/wp-booster/wp-admin/tagdiv-view-welcome.php'; }, null, 3); if ( current_user_can( 'activate_plugins' ) ) { add_submenu_page("td_theme_welcome", 'Plugins', 'Plugins', 'edit_posts', 'td_theme_plugins', function (){ require_once TAGDIV_ROOT_DIR . '/includes/wp-booster/wp-admin/tagdiv-view-theme-plugins.php'; } ); } $is_white_label = defined('TD_COMPOSER') ? td_util::get_option('tds_white_label') : 'no'; if ('enabled' !== $is_white_label) { add_submenu_page("td_theme_welcome", 'Support', 'Support', 'edit_posts', 'td_theme_support', function () { require_once TAGDIV_ROOT_DIR . '/includes/wp-booster/wp-admin/tagdiv-view-support.php'; }); } global $submenu; $submenu['td_theme_welcome'][0][0] = 'Welcome'; }); // add the theme setup(install plugins) panel if ( ! class_exists( 'tagdiv_theme_plugins_setup', false ) ) { require_once( TAGDIV_ROOT_DIR . '/includes/wp-booster/wp-admin/plugins/class-tagdiv-theme-plugins-setup.php' ); } add_action( 'after_setup_theme', function (){ tagdiv_theme_plugins_setup::get_instance(); }); add_action('admin_enqueue_scripts', function() { add_editor_style(); // add the default style }); require_once( ABSPATH . 'wp-admin/includes/file.php' ); WP_Filesystem(); } } Delhi HC order spotlights non-animal techniques in research – Modern Business Times
Home News Delhi HC order spotlights non-animal techniques in research

Delhi HC order spotlights non-animal techniques in research

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Delhi HC order spotlights non-animal techniques in research

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A recent Delhi High Court order, on inspecting facilities using animals for the development of antitoxins, has put the spotlight on non-animal methods that could help replace the use of horses and other animals in developing serum products such as antitoxins and antivenins.

In a petition filed by the People for the Ethical Treatment of Animals (PETA), the Delhi HC directed the CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals) and other government bodies to continue routine inspections to assess animal welfare and well-being, and to initiate action against defaulting establishments under existing laws and regulations.

The order also directed CPCSEA to consider recommendations made by the petitioner and implement them, wherever possible. “Specifically, the adoption of the latest scientific methodologies for antibody production be encouraged wherever feasible. The CPCSEA is hereby directed to consider the proposals put forth by the petitioner in this petition, effectuating them where deemed appropriate,” the directive said.

While the CPCSEA has to ensure the well-being of animals involved in research, without impeding the production of life-saving products, the order observed, “we can also not be oblivious to the dawn of cutting-edge, non-animal-centric techniques for antibody generation. Such advancements suggest a trajectory that these establishments might, and arguably should, consider in the right earnest..” It further emphasised, “the responsibility was on supervisory bodies to not just delve into these contemporary methodologies but to earnestly integrate them, thereby diminishing reliance on equines.”

The CPCSEA, now Committee for Control and Supervision of Experiments on Animals (CCSEA), is constituted under the Prevention of Cruelty to Animals (PCA) Act, 1960. 

Pointing to the plight of horses, for example, used in facilities for the production of serum (a component of the animals’ blood that’s used to make medicines and other biomedical products), Ankita Pandey, PETA (India) Science Policy Advisor, told businessline that they were drafting recommendations for the CPCSEA, as directed by the court for a “constructive roadmap” for appropriate action. While PETA has been advocating non-animal methods, including recombinant technology, that could replace horses and other animals used in the production of such products, she said, in the interim, horses in the facilities needed to be better looked after and the long-suffering equines needed to be sent to a sanctuary for veterinary care, “where they can begin to recover from the psychological trauma of being used as blood factories”.

“Go beyond the surface”

The court observed that the CPCSEA (CCSEA) needed to go “beyond the surface” and that there was “discernible room for amplification and enhancement” in the steps they were taking. This was said, given that earlier inspection reports prepared by the Animal Welfare Board of India (AWBI), a government body, had revealed that horses being used were found sick, injured, frightened, and dying.

“Antitoxin generation using animal immunisation presents scientific and ethical concerns. The use of unwell animals for antitoxin production is dangerous for the animals and for the humans who receive these medicines made from animal blood. Any product made from animal blood may cause life-threatening allergic reactions and serum sickness and carries the risk of transmitting pathogens from animals to humans,” says Pandey.

Citing the PETA Science Consortium International-funded development of a recombinant diphtheria antitoxin that did not require a single horse to endure a life of painful procedures in serum-production facilities, Pandey said, they were in discussions with industry representatives and regulatory authorities to popularise animal-free alternatives.

Calling on CPCSEA (CCSEA) to be relentless in its efforts, the court said, “The envisioned future should be a system that is not only more compassionate but is technologically advanced, efficient, and, most importantly, truly resonates with both the letter and spirit of the PCA Act.”



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